134905-46-7Relevant academic research and scientific papers
Synthesis of Amino-β-lactams by the Photolytic Reaction of Imines with Pentacarbonylchromium(0)
Borel, Christian,Hegedues, Louis S.,Krebs, Jurg,Satoh, Yoshitaka
, p. 1101 - 1105 (1987)
Chromium-carbene complexes containing the group were synthesized by the reaction of Vilsmeir's salts with Cr(CO)52-.These carbenes were remarkably air stable and resistant to attack by nucleophiles.Photolytic reaction of these complexes with imines, oxazines, oxazolines, imidates, thiazines, and thiazolines produced β-lactams in fair to good yield.In most cases trans stereochemistry was observed.Representative dibenzylamino-β-lacatms were debenzylated to produce β-lactams having a free NH2 group α to the lactam carbonyl group.
