1349151-98-9

Usage

Uses

Used in Pharmaceutical Industry:
1-Isopropyl-6-oxo-1,6-dihydropyridine-3-boronic Acid Pinacol Ester is used as a synthetic reagent for the production of various drugs. Its role in coupling reactions allows for the creation of complex molecular structures that are essential in medicinal chemistry, contributing to the development of new pharmaceuticals.
Used in Agrochemical Industry:
In the agrochemical sector, 1-Isopropyl-6-oxo-1,6-dihydropyridine-3-boronic Acid Pinacol Ester serves as a key intermediate in the synthesis of pesticides. Its reactivity in organic synthesis aids in the production of effective compounds for pest control, enhancing crop protection strategies.
Used in Material Science:
1-Isopropyl-6-oxo-1,6-dihydropyridine-3-boronic Acid Pinacol Ester has potential applications in the development of new materials. Its unique properties as a boron-containing compound can be leveraged to create innovative materials with specific characteristics for various applications.
Used as a Building Block in Organic Synthesis:
1-Isopropyl-6-oxo-1,6-dihydropyridine-3-boronic Acid Pinacol Ester is also used as a building block in the synthesis of complex organic molecules. Its versatility in forming carbon-carbon bonds makes it a valuable component in the assembly of intricate organic structures for research and industrial applications.

Upstream product

• 851087-08-6 5-bromo-1-isopropylpyridine-2(1H)-one 
• 73183-34-3 bis(pinacol)diborane 
• 13466-38-1 5-bromopyridin-2-ol 
• 13466-38-1 5-bromopyridin-2(1H)-one 

Downstream Products

• 1349731-37-8 5-[5-amino-6-[5-[2-methyl-4-[[[(3S)-tetrahydrofuran-3-yl]amino]methyl]phenyl]-1,3,4-oxadiazol-2-yl]pyrazin-2-yl]-1-isopropylpyridin-2-one 
• 1349731-96-9 5-[5-amino-6-[5-[3-(methylaminomethyl)phenyl]-1,3,4-oxadiazol-2-yl]pyrazin-2-yl]-1-isopropylpyridin-2-one 
• 1349734-33-3 5-[5-amino-6-[5-[3-(bromomethyl)phenyl]-1,3,4-oxadiazol-2-yl]pyrazin-2-yl]-1-isopropylpyridin-2-one 
• 1349734-28-6 tert-butyl N-[3-[5-[4-(bromomethyl)-2-methylphenyl]-1,3,4-oxadiazol-2-yl]-5-(1-isopropyl-6-oxo-3-pyridyl)pyrazin-2-yl]-N-tert-butoxycarbonylcarbamate 
• 1349734-31-1 tert-butyl N-[3-[5-[3-(bromomethyl)phenyl]-1,3,4-oxadiazol-2-yl]-5-(1-isopropyl-6-oxo-3-pyridyl)pyrazin-2-yl]-N-tert-butoxycarbonylcarbamate 
• 1349151-75-2 5-(5-amino-6-(benzyloxy)pyrazin-2-yl)-1-isopropylpyridin-2(1H)-one 
• 1350351-14-2 5-[5-amino-6-[2-(3-hydroxyphenyl)ethynyl]pyrazin-2-yl]-1-isopropyl-pyridin-2-one 

Relevant academic research and scientific papers

TRIAZOLO-PYRIMIDINE COMPOUNDS AND USES THEREOF

The present disclosure relates to novel triazolo-pyrimidine compounds targeting adenosine receptors (especially A1 and A2, particularly A2a). The present disclosure also relates to pharmaceutical compositions comprising one or more of the compounds as an active ingredient, and use of the compounds in the treatment of adenosine receptor (AR) associated diseases, for example cancer such as NSCLC, RCC, prostate cancer, and breast cancer.

PYRIDINONE DERIVATIVES AND THEIR USE AS SELECTIVE ALK-2 INHIBITORS

The invention relates to a compound of Formula I or a pharmaceutically acceptable salt thereof, a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.

Substituted arylamine compound as well as preparation method and purpose thereof

The invention relates to a substituted arylamine compound as well as a preparation method and a purpose thereof, and particularly relates to the substituted arylamine compound, a pharmacologically acceptable salt, a stereisomer, a polymorphic substance, a

Substituted thiazole derivative and application thereof

The invention provides a compound represented by a general formula (I), or a stereoisomer, pharmaceutically acceptable salt, solvate, hydrate, chemically protective form or prodrug thereof. The compound has an effect of inhibiting adenosine receptor 2a (A2a), and can be used as an antagonist of the adenosine receptor 2a (A2A) for treating tumors.

COMPOUNDS USEFUL AS INHIBITORS OF ATR KINASE

The present invention relates to pyrazine and pyridine compounds useful as inhibitors of ATR protein kinase. The invention also relates to pharmaceutically acceptable compositions comprising the compounds of this invention; methods of treating various dis

COMPOUNDS USEFUL AS INHIBITORS OF ATR KINASE

The present invention relates to pyrazine and pyridine compounds useful as inhibitors of ATR protein kinase. The invention also relates to pharmaceutically acceptable compositions comprising the compounds of this invention; methods of treating various diseases, disorders, and conditions using the compounds of this invention; processes for preparing the compounds of this invention; intermediates for the preparation of the compounds of this invention; and methods of using the compounds in in vitro applications, such as the study of kinases in biological and pathological phenomena; the study of intracellular signal transduction pathways mediated by such kinases; and the comparative evaluation of new kinase inhibitors. The compounds of this invention have formula I wherein the variables are as defined herein.