134916-75-9Relevant academic research and scientific papers
CARBON-CARBON BOND FORMATION AND KETENIMINE SYNTHESIS FROM N-PHENYL IMIDOTHIOESTERS.
Lage, Nadia,Masson, Serge,Thuillier, Andre
, p. 141 - 144 (2007/10/02)
Methyl N-phenyl ethanimidothioate 1 and its α-silylated homologue 2 are metallated into lithiated enaminates which can be regioselectively monoalkylated at -78 deg C on the α-carbon atom.Imidothioester 2, treated at higher temperatures by 2 equivalents of BuLi, leads, after alkylation or hydrolysis, to stable silylated N-phenyl ketenimines.Formation of ketenimines are also observed by flash thermolysis of 2 or of the silylated S,N-ketene acetal 10.
