1349171-32-9

Basic information

• Product Name: 2-[5-methoxycarbonyl-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]pyridine
• Synonyms: 2-[5-methoxycarbonyl-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]pyridine
• CAS NO: 1349171-32-9
• Molecular Weight: 339.199
• Mol File: 1349171-32-9.mol

Chemical Properties

• CAS DataBase Reference: 2-[5-methoxycarbonyl-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[5-methoxycarbonyl-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]pyridine(1349171-32-9)
• EPA Substance Registry System: 2-[5-methoxycarbonyl-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]pyridine(1349171-32-9)

Safety Data

• Hazardous Substances Data: 1349171-32-9(Hazardous Substances Data)

Upstream product

• 109-04-6 2-bromo-pyridine 
• 99769-19-4 [3-(methoxycarbonyl)phenyl]boronic acid 
• 98061-20-2 3-pyridin-2-yl-benzoic acid methyl ester 
• 73183-34-3 bis(pinacol)diborane 

Relevant articles and documents

N-heterocyclic carbene enabled rhodium-catalyzed ortho C(sp2)-H borylation at room temperature

We report a rhodium-catalyzed ortho C(sp2)-H borylation of 2-phenylpyridines using commercially available N-heterocyclic carbenes (NHCs) as ligand and pinacolatodiboron (B2pin2) as borylating reagent. The reaction could take place at room temperature, tolerating a wide range of functionalities and affording ortho borylated products in moderate to excellent yields. The current method is also applicable to gram-scale reaction with reduced catalyst loading.

Ruthenium catalysed C-H bond borylation

An easily prepared series of phenylindenyldihydridosilyl ruthenium complexes (2a-2d) was obtained by reaction of tertiary silanes with the commercially-available [RuCl(3-phenylindenyl)(PPh3)2] (1). The [RuH2(3-phenylindeny

Rh-catalyzed ortho -selective C-H borylation of N-functionalized arenes with silica-supported bridgehead monophosphine ligands

Supported phosphine-Rh systems, prepared in situ from silica-supported bridgehead monophosphines and [Rh(OH)(cod)]2, have enabled ortho-selective C-H borylation for a range of arenes containing nitrogen-based directing groups. The regioselectivity was excellent with various N-directing groups, including saturated and unsaturated N-heterocycles, tert-aminoalkyl groups, and imine-type C-N double bonds. The reaction showed significant tolerance toward steric repulsion around the reacting C-H bond. This Rh catalysis complements the Ir-catalyzed ortho-borylation, which is effective for arenes with oxygen-based directing groups.