1349171-36-3

Basic information

• Product Name: N-(1-hydroxy-2-methylpropan-2-yl)-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide
• Synonyms: N-(1-hydroxy-2-methylpropan-2-yl)-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide
• CAS NO: 1349171-36-3
• Molecular Weight: 319.209
• Mol File: 1349171-36-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-(1-hydroxy-2-methylpropan-2-yl)-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(1-hydroxy-2-methylpropan-2-yl)-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide(1349171-36-3)
• EPA Substance Registry System: N-(1-hydroxy-2-methylpropan-2-yl)-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide(1349171-36-3)

Safety Data

• Hazardous Substances Data: 1349171-36-3(Hazardous Substances Data)

Upstream product

• 19312-06-2 4,5-dihydro-4,4-dimethyl-2-phenoxazole 
• 73183-34-3 bis(pinacol)diborane 

Relevant articles and documents

Rh-catalyzed ortho -selective C-H borylation of N-functionalized arenes with silica-supported bridgehead monophosphine ligands

Supported phosphine-Rh systems, prepared in situ from silica-supported bridgehead monophosphines and [Rh(OH)(cod)]2, have enabled ortho-selective C-H borylation for a range of arenes containing nitrogen-based directing groups. The regioselectivity was excellent with various N-directing groups, including saturated and unsaturated N-heterocycles, tert-aminoalkyl groups, and imine-type C-N double bonds. The reaction showed significant tolerance toward steric repulsion around the reacting C-H bond. This Rh catalysis complements the Ir-catalyzed ortho-borylation, which is effective for arenes with oxygen-based directing groups.