1349184-68-4

Upstream product

• 1349184-67-3 N-((1S,3S)-3-((3-chloropyrazin-2-yl)oxy)cyclobutyl)quinolin-2-amine 
• 375853-82-0 tert-Butyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,6-dihydro-1(2H)-pyridinecarboxylate 
• 612-62-4 2-Chloroquinoline 
• 1349184-48-0 (1S,3S)-3-((3-chloropyrazin-2-yl)oxy)cyclobutanamine hydrochloride 
• 1349184-47-9 tert-butyl ((1S,3S)-3-((3-chloropyrazin-2-yl)oxy)cyclobutyl)carbamate 

Downstream Products

• 1349184-71-9 tert-butyl 4-(3-((1S,3S)-3-(quinolin-2-ylamino)cyclobutoxy)pyrazin-2-yl)piperidine-1-carboxylate 

Relevant academic research and scientific papers

HETEROARYLOXYCARBOCYCLYL COMPOUNDS AS PDE10 INHIBITORS

Heteroaryloxycarbocyclyl compounds of formula (I), and compositions containing them, and processes for preparing such compounds. Provided herein also are methods of treating disorders or diseases treatable by inhibition of PDE10, such as obesity, non-insulin dependent diabetes, schizophrenia, Huntington's Disease, bipolar disorder, obsessive -compulsive disorder, and the like. Formula (I)