134920-91-5Relevant academic research and scientific papers
ENANTIOSELEKTIVE KATALYSE, 63 - OPTISCH AKTIVE PHOSPHINE AUS DICARBONSAEUREN UND IHR EINSATZ IN DER ENANTIOSELEKTIVEN HYDRIERUNG
Brunner, H.,Zettlmeier, W.
, p. 259 - 265 (2007/10/02)
Two optically active bident phosphine ligands were synthesized from derivatives of succinic acid as starting materials.The optical resolution of the acids was carried out with cinchonidine and (S)-α-phenylethylamine.In the Rh-catalyzed enantioselective hydrogenation of α-acetamidocinnamic acid, the bisphosphine with a phenyl substituent in the 2-position of the four-carbon chain gave enantiomeric excess of 17percent.The enantiomeric excess was twice as high with the corresponding thienyl substituted biphosphine.
