134924-12-2Relevant academic research and scientific papers
[a]-Anellated Carbazoles with Antitumor Activity: Synthesis and Cytotoxicity
Rogge,Fischer,Pindur,Schollmeyer
, p. 97 - 102 (2007/10/03)
The cycloadducts 3, 5, and 7, readily available from methoxy-substituted 3-vinylindoles 1 and 2, were dehydrogenated with DDQ to the coplanar [a]-anellated carbazoles 4, 6, and 8. Compound 4a, also characterized by X-ray structural analysis, shows signifi
New Diels-Alder Reactions of (E/Z)-2'-Methoxy-Substituted 3-Vinylindoles with Carbo- and Heterodienophiles: Regio- and Stereoselective Access to Annelated Indoles and Functionalized or Annelated Carbazoles
Pindur, Ulf,Kim, Myung-Hwa,Rogge, Martina,Massa, Werner,Molinier, Michel
, p. 910 - 915 (2007/10/02)
The (E/Z)-2'-methoxy-substituted 3-vinylindoles 1a,b react with some carbo- and azodienophiles to furnish new carbazoles and pyridazinoindoles.The conservation of the E and Z stereochemistry of 1 in these Diels-Alder reactions was investigated, and a mech
Diels-Alder Reactions of Vinylindoles with Aryne and 1,4-Benzoquinones: New Potential DNA Intercalators
Pindur, Ulf,Pfeuffer, Ludwig,Eitel, Manfred,Rogge, Martina,Haber, Manfred
, p. 291 - 298 (2007/10/02)
Diels-Alder reactions of 2- and 3-vinylindoles with aryne, 1,4-benzo- and 1,4-naphthoquinone lead to new six-ring annellated carbazoles.Molecular modeling studies predict that the compounds with coplanar framework are able to intercalate with the B-DNA.
