13494-38-7Relevant articles and documents
Silica gel catalyzed synthesis of quinoxialine 1,4-dioxides under solvent-free conditions using microwave irradiation
Sumiyoshi, Yusuke,Saito, Hiroaki,Miyairi, Shinichi,Takabatake, Tohru
scheme or table, p. 905 - 909 (2009/09/29)
We report on the simple and quick synthesis of quinoxaline 1,4-dioxides in solvent-free conditions under microwave irradiation. Heating of various benzofuroxans and β-ketoesters or 1,3-diketones adsorbed on silica gel in a microwave oven for two minutes affords diverse biologically attractive quinoxaline 1,4-dioxides in high to excellent yields. Silica gel functions not only as support using microwave but also as catalyst and dehydration reagent.
The reactions of benzofuroxan with carbonyl compounds on the surface of solid catalysts
Takabatake,Hasegawa,Hasegawa
, p. 1477 - 1480 (2007/10/02)
The cyclocondensations of benzofuroxan 1a with carbonyl compounds were smoothly and efficiently carried out by the adsorption of the components on the surface of silica gel or a molecular sieve to form a 2,3-disubstituted quinoxaline 1,4-dioxide. When the
Reactions of Benzofuroxan with 1,3-Diketones or β-Ketoesters on Silica Gel or Alumina
Hasegawa, Minoru,Takabatake, Tohru
, p. 938 (2007/10/02)
The cyclocondensation of benzofuroxan with 1,3-diketones, 3-oxoalkanoic esters, butanedioic esters, or 3-oxoalkanamides in the presence of silica gel (adsorption of the components on silica gel) represents a convenient method for the synthesis of 2,3-disu
