134959-20-9Relevant academic research and scientific papers
Α, β, β-trifluorolactic of industrial manufacturing method (by machine translation)
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Paragraph 0050-0055, (2018/12/12)
PROBLEM TO BE SOLVED: To provide a method of producing industrially α,β,β-trifluorostyrenes. SOLUTION: The method of producing industrially the α,β,β-trifluorostyrenes includes a dehydrofluorination step of reacting α-aryl-α,β,β,β-tetrafluoroethanes with an alkali metal-bis(trimethylsilyl) amide, in the production of α,β,β-trifluorostyrenes, and an after-treatment step executed followed thereto to react a mixture containing the α,β,β-trifluorostyrenes of objective products and bis-(trimethylsilyl) amine of a byproduct with hydrogen fluoride, or a salt or a complex comprising an organic base and hydrogen fluoride. COPYRIGHT: (C)2012,JPO&INPIT
Copper-mediated one-pot synthesis of trifluorostyrene derivatives from tetrafluoroethylene and arylboronate
Kikushima, Kotaro,Sakaguchi, Hironobu,Saijo, Hiroki,Ohashi, Masato,Ogoshi, Sensuke
supporting information, p. 1019 - 1021 (2015/08/24)
We developed the copper-mediated synthesis of trifluorostyrene derivatives. β-Fluorine elimination of a 2-aryl-1,1,2,2- tetrafluoroethylcopper complex, generated in situ from arylboronate, copper tert-butoxide, and 1,10-phenanthroline with tetrafluoroethylene (TFE) via carbocupration, was promoted by the addition of a Lewis acid. The present reaction system was applied to the one-pot synthesis of various trifluorostyrene derivatives, through the transmetalationcarbocuprationβ-fluorine elimination sequence.
Room temperature preparation of trifluoroethenylzinc reagent by metalation of the readily available halocarbon HFC-134a and an efficient, economically viable synthesis of 1,2,2-trifluorostyrenes
Raghavanpillai, Anilkumar,Burton, Donald J.
, p. 7083 - 7091 (2007/10/03)
Trifluoroethenylzinc reagent [CF2=CFZnX] was generated from the readily available halocarbon HFC-134a by an in situ metalation-transmetalation procedure at temperatures near to room temperature (15-20 °C). By systematic standardization of the m
A remarkable room temperature preparation of the trifluorovinylzinc reagent from HFC-134a. A cost-effective, high yield synthesis of α,β,β-trifluorostyrenes
Anilkumar,Burton, Donald J
, p. 2731 - 2733 (2007/10/03)
The reaction of LDA (2.0 equiv.) with a THF solution of ZnCl2 (1.0 equiv.) and CF3CFH2 (HFC-134a) (1.2 equiv.) at 15-20°C gives a 73% yield of [F2C=CFZnCl]. Addition of R-C6H4I and Pd(PPhs
