134965-75-6Relevant academic research and scientific papers
5-Amino-3-imino-2,3-dihydrofurans and 3-Amino-5-imino-2,5-dihydrofurans from 4,4-Dialkyl-4-hydroxybut-2-ynenitriles
Landor, Stephen R.,Asobo, P. Forche,Fomum, Z. Tanee,Roberts, Ralph
, p. 1201 - 1204 (2007/10/02)
A novel general synthesis of the dihydrofurans 4 and 3b with nitrogen substituents in the 3- and 5-positions from 4,4-dialkyl-4-hydroxybut-2-ynenitriles 1 and primary and secondary amines is described.A 5-amino group reacts further with unchanged, or an excess of, hydroxybutynenitrile to give the difurylimines 6.
