1349680-27-8

Basic information

• Product Name: (E)-3-[1-([1,1'-Biphenyl]-4-ylcarbonyl)-2,3,4,5-tetrahydro-1H-1-benzazepin-8-yl]-N,N-dimethyl-2-propen-1-amine Hydrochloride
• Synonyms: (E)-3-[1-([1,1'-Biphenyl]-4-ylcarbonyl)-2,3,4,5-tetrahydro-1H-1-benzazepin-8-yl]-N,N-dimethyl-2-propen-1-amine Hydrochloride
• CAS NO: 1349680-27-8
• Molecular Weight: 447.02
• Mol File: 1349680-27-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (E)-3-[1-([1,1'-Biphenyl]-4-ylcarbonyl)-2,3,4,5-tetrahydro-1H-1-benzazepin-8-yl]-N,N-dimethyl-2-propen-1-amine Hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-3-[1-([1,1'-Biphenyl]-4-ylcarbonyl)-2,3,4,5-tetrahydro-1H-1-benzazepin-8-yl]-N,N-dimethyl-2-propen-1-amine Hydrochloride(1349680-27-8)
• EPA Substance Registry System: (E)-3-[1-([1,1'-Biphenyl]-4-ylcarbonyl)-2,3,4,5-tetrahydro-1H-1-benzazepin-8-yl]-N,N-dimethyl-2-propen-1-amine Hydrochloride(1349680-27-8)

Safety Data

• Hazardous Substances Data: 1349680-27-8(Hazardous Substances Data)

Upstream product

• 374813-05-5 (E)-N,N-Dimethyl-3-(2,3,4,5-tetrahydro-1H-1-benzazepin-8-yl)-2-propen-1-amine 
• 14002-52-9 o-phenylbenzoyl chloride 
• 32503-27-8 tetra(n-butyl)ammonium hydrogensulfate 

Relevant articles and documents

Melanin-concentrating hormone antagonist

A melanin-concentrating hormone antagonist comprising a compound of the formula: wherein R is hydrogen atom or a cyclic group which may be substituted; X is a bond or a spacer having a main chain of 1 to 10 atoms; Y is a spacer having a main chain of 1 to 6 atoms; ring A is benzene ring which may be further substituted; ring B is a 5- to 9-membered nitrogen-containing non-aromatic heterocyclic ring which may be further substituted; R1 and R2 are the same or different and are hydrogen atom, a hydrocarbon group which may be substituted or a heterocyclic group which may be substituted; or R1 and R2, together with the adjacent nitrogen atom, may form a nitrogen-containing heterocyclic ring which may be substituted; or R2, together with the adjacent nitrogen atom and Y, may form a nitrogen-containing heterocyclic ring which may be substituted; or a salt thereof is useful as a preventive or therapeutic agent for obesity, etc.