134970-53-9Relevant academic research and scientific papers
Organocatalytic ?±-addition of isocyanides to aldehydes
Yamada, Takeshi,Hirose, Tomoyasu,O??mura, Satoshi,Sunazuka, Toshiaki
supporting information, p. 296 - 301 (2015/03/04)
?±-Hydroxyamide is an important chemical component widely observed in biologically active natural products. One of the most direct methods to access a ?±-hydroxyamide is the Passerini-type reaction. However, this catalytic process was limited. Herein, we
Biocatalytic reduction of α-keto amides to (R)-α-hydroxy amides using Candida parapsilosis ATCC 7330
Stella, Selvaraj,Chadha, Anju
, p. 345 - 352 (2013/01/15)
Biocatalytic reduction of primary and secondary α-keto amides was accomplished using whole cells of Candida parapsilosis ATCC 7330. The primary (R)-α-hydroxy amides were obtained in good enantiomeric excess (up to 94%) and conversion (88-99%) as compared to the secondary (R)-α-hydroxy amides.
Borinic acid catalyzed α-addition to isocyanide with aldehyde and water
Soeta, Takahiro,Kojima, Yuuki,Ukaji, Yutaka,Inomata, Katsuhiko
supporting information; experimental part, p. 2557 - 2559 (2011/06/21)
A first example of diphenylborinic acid catalyzed α-addition to isocyanide with aldehyde and water is described. The reaction proceeded smoothly in the presence of water and 5 mol % of borinic acid to give the corresponding α-hydroxyamides in good to high
1-Chloroalkyl p-Tolyl Sulfoxides as Useful Agents for Homologation of Carbonyl Compounds: Conversion of Carbonyl Compounds to α-Hydroxy Acids, Esters, and Amides and α,α'-Dihydroxy Ketones
Satoh, Tsuyoshi,Onda, Ken-ichi,Yamakawa, Koji
, p. 4129 - 4134 (2007/10/02)
One-carbon homologation of carbonyl compounds to α-hydroxy acids, esters, and amides by the use of 1-chloroalkyl p-tolyl sulfoxide as a hydroxycarbonyl anion equivalent is reported.Oxidation of the vinyl chlorides, the intermediates of the above-mentioned
