134978-28-2

Upstream product

• 117285-92-4 (R)-3-Benzyloxy-4-(S)-oxiranyl-butyric acid benzyl ester 

Downstream Products

• 209340-30-7 (S)-2-((S)-2-Benzyloxy-4-trityloxy-butyl)-oxirane 
• 209340-32-9 (S)-2-[(S)-2-Benzyloxy-4-(4-methoxy-phenoxy)-butyl]-oxirane 
• 209340-34-1 (2S,4S)-4-Benzyloxy-1-[1,3]dithian-2-yl-2-methyl-6-trityloxy-hexan-2-ol 
• 209340-38-5 (2S,4S)-4-Benzyloxy-1-{2-[(S)-2-(tert-butyl-dimethyl-silanyloxy)-2-methyl-3-((S)-2-phenyl-[1,3]dioxan-4-yl)-propyl]-[1,3]dithian-2-yl}-6-(4-methoxy-phenoxy)-hexan-2-ol 
• 209340-33-0 (S)-4-Benzyloxy-1-[1,3]dithian-2-yl-6-trityloxy-hexan-2-one 
• 209340-36-3 tert-Butyl-[(S)-1-[1,3]dithian-2-ylmethyl-1-methyl-2-((S)-2-phenyl-[1,3]dioxan-4-yl)-ethoxy]-dimethyl-silane 
• 209340-35-2 (S)-1-[1,3]Dithian-2-yl-2-methyl-3-((S)-2-phenyl-[1,3]dioxan-4-yl)-propan-2-ol 

Relevant academic research and scientific papers

Synthetic studies on altohyrtins (spongistatins): Synthesis of the C1- C14 (AB) spiroacetal portion

The C1-C14 portion of altohyrtins (spongistatins) was prepared in a convergent manner from 3,4,6-tri-O-acetyl-D-glucal via a chelation-controlled methylation of ketone, dithiane couplings with epoxides, and a thermodynamically-controlled spitoacetalization.