134993-12-7

Basic information

• Product Name: (2S,3R,5S,8aR)-2,3-Diphenyl-hexahydro-oxazolo[3,2-a]pyridine-5-carbonitrile
• CAS NO: 134993-12-7
• Molecular Weight: 304.392
• Mol File: 134993-12-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2S,3R,5S,8aR)-2,3-Diphenyl-hexahydro-oxazolo[3,2-a]pyridine-5-carbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: (2S,3R,5S,8aR)-2,3-Diphenyl-hexahydro-oxazolo[3,2-a]pyridine-5-carbonitrile(134993-12-7)
• EPA Substance Registry System: (2S,3R,5S,8aR)-2,3-Diphenyl-hexahydro-oxazolo[3,2-a]pyridine-5-carbonitrile(134993-12-7)

Safety Data

• Hazardous Substances Data: 134993-12-7(Hazardous Substances Data)

Upstream product

• 23364-44-5 (1S,2R)-2-Amino-1,2-diphenylethanol 
• 151-50-8 potassium cyanide 
• 111-30-8 Glutaraldehyde 

Downstream Products

• 134993-13-8 (2S,3R,5S,8aR)-2,3-Diphenyl-5-propyl-hexahydro-oxazolo[3,2-a]pyridine-5-carbonitrile 
• 134993-14-9 (2S,3R,5S,8aR)-2,3-Diphenyl-5-propyl-hexahydro-oxazolo[3,2-a]pyridine 
• 134993-15-0 (1S,2R)-2-((2R,6S)-2-Methyl-6-propyl-piperidin-1-yl)-1,2-diphenyl-ethanol 

Relevant articles and documents

Asymmetric synthesis XXIII. A 100% cis diastereoselectivity in the synthesis of enantiomerically pure 2,6-dialkylpiperidines

Enantiomerically pure (+)-(2S,6R)-2-propyl-6-methyl-piperidine 6 has been obtained in 4 steps, 66% overall yield and without separation of diastereomers from the chiral 2-cyano-6-oxazolopiperidine synthon 1c derived from (+)-1,2-diphenyl-2-aminoethanol.