135-35-3

Basic information

• Product Name: Chlorothen hydrochloride
• Synonyms: Chlorothen hydrochloride
• CAS NO: 135-35-3
• Molecular Formula: C14H19Cl2N3S
• Molecular Weight: 332.29176
• Mol File: 135-35-3.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 408.8°Cat760mmHg
• Flash Point: 201°C
• Appearance: /
• Density: 1.234g/cm³
• CAS DataBase Reference: Chlorothen hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: Chlorothen hydrochloride(135-35-3)
• EPA Substance Registry System: Chlorothen hydrochloride(135-35-3)

Safety Data

• Hazardous Substances Data: 135-35-3(Hazardous Substances Data)

Usage

General Description

Chlorothen hydrochloride, also known as metirosine, is a chemical compound that acts as an inhibitor of tyrosine hydroxylase, an enzyme involved in the production of dopamine and other catecholamines. It is used to treat pheochromocytoma, a rare tumor of the adrenal gland that produces excessive amounts of catecholamines, and as an investigational drug for the treatment of other conditions such as post-traumatic stress disorder and substance use disorders. Chlorothen hydrochloride works by blocking the synthesis of catecholamines, which helps to reduce the symptoms of excessive catecholamine production in pheochromocytoma and may have potential therapeutic effects in other disorders related to catecholamine dysregulation. However, it can also cause side effects such as low blood pressure, fatigue, and depression, and should be used with caution under the supervision of a healthcare professional.