135018-63-2

Upstream product

• 135018-62-1 3-ethyl 5-methyl 2-amino-4-(4-fluorophenyl)-6-(1-methylethyl)-3,5-pyridinedicarboxylic acid 

Downstream Products

• 140918-68-9 5-(4-Fluorophenyl)-7-isopropyl-6-methoxycarbonyl-2-oxo-1,4-dihydro-2H-pyrido-[2,3-d][1,3]oxazine 
• 849470-83-3 C₁₇H₁₉FN₂O₂ 

Relevant academic research and scientific papers

PYRIMIDINE AND PYRIDINE DERIVATIVES USEFUL AS HMG-COA REDUCTASE INHIBITORS AND METHOD OF PREPARATION THEREOF

Compounds are provided having the following structure which are HMG CoA reductase inhibitors and thus are active in inhibiting cholesterol biosynthesis, modulating blood serum lipids, for example, lowering LDL cholesterol and/or increasing HDL cholesterol

SUBSTITUTED PYRIDO-OXAZINE INHIBITORS OF HMG-COA REDUCTASE

Substituted pyrido-oxazines can be prepared by reduction of the corresponding ketones. They are useful active compounds in medicaments, in particular for the treatment of hyperlipoproteinaemia, lipoproteinaemia and arteriosclerosis.

HMG-COA REDUCTASE-INHIBITING SUBSTITUTED AMINO-PYRIDINES

HMG-COA reductase-inhibiting compounds of the formula STR1 in which X represents a group of the formula--CH 2--CH 2--or--CH=CH--,R represents a group of the formula STR2 R 1 represents optionally substituted aryl, R 2 represe