135026-90-3

Basic information

• Product Name: 7-{(3R)-3-[(1S)-1-aminoethyl]pyrrolidin-1-yl}-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid
• CAS NO: 135026-90-3
• Molecular Formula: C₁₈H₂₁FN₄O₃
• Molecular Weight: 360.3827
• Mol File: 135026-90-3.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 593.3°C at 760 mmHg
• Flash Point: 312.6°C
• Density: 1.467g/cm³
• Vapor Pressure: 6.36E-15mmHg at 25°C
• Refractive Index: 1.661
• CAS DataBase Reference: 7-{(3R)-3-[(1S)-1-aminoethyl]pyrrolidin-1-yl}-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 7-{(3R)-3-[(1S)-1-aminoethyl]pyrrolidin-1-yl}-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid(135026-90-3)
• EPA Substance Registry System: 7-{(3R)-3-[(1S)-1-aminoethyl]pyrrolidin-1-yl}-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid(135026-90-3)

Safety Data

• Hazardous Substances Data: 135026-90-3(Hazardous Substances Data)

Upstream product

• 107258-90-2 3-[1-(N-tert-butoxycarbonylamino)ethyl]pyrrolidine 
• 100361-18-0 7-chloro-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydro-[1,8]naphthyridine-3-carboxylic acid 
• 7440-57-5 gold 

Relevant articles and documents

Naphthyridine antibacterial agents

Novel naphthyridine-carboxylic acids as antibacterial agents are described as well as methods for their manufacture, formulation, and use in treating bacterial infections.

Pyridonecarboxylic acid derivatives

This invention provides novel pyridonecarboxylic acid derivatives having a quite high antimicrobial activity. The derivatives have the following formula: STR1 wherein R1, R2 and R3 represent each a hydrogen or C1 -C6 alkyl group; R4 represents an ethyl, 2-fluoroethyl, vinyl, isopropyl, isopropenyl or cyclopropyl group; and X represents CH, C-F, C-Cl or N wherein (i) one of R1, R2 and R3 represents a hydrogen or C1 -C6 alkyl group, and (ii) either R1 forms a methylene chain having 2 to 4 carbon atoms together with R2 or R3, or R2 and R3 form together an alkylene chain having 2 to 5 atoms and R4 represents an ethyl, 2-fluorethyl, vinyl, isopropyl, isopropenyl or cyclopropyl group and X represents CH, C-F, or C-Cl and salt thereof.