1350294-01-7

Upstream product

• 1350294-09-5 3-(2-chlorophenyl)-4-amino-5-hydrazino 1,2,4-triazole 
• 91-56-5 indole-2,3-dione 
• 13229-02-2 4-amino-5-(2-chlorophenyl)-4H-1,2,4-triazole-3-thiol 

Downstream Products

• 1437318-86-9 C₂₄H₁₆ClFeN₈O₄*H₂O 

Relevant academic research and scientific papers

Synthesis, spectral characterization and in vitro antifungal activity of lanthanum(III) and praseodymium(III) complexes with Schiff bases derived from 5-substituted-4-amino-5-hydrazino-1,2,4-triazoles and isatin

The new lanthanum(III) and praseodymium(III) complexes of the general formula [LnCl(L)(H2O)2] (Ln = LaIII or Pr III; H2L = Schiff bases derived from 3-substituted-4- amino-5-hydrazino-1,2,4-triazoles

Antioxidant, tautomerism and antibacterial studies of Fe(III)-1,2,4- triazole based complexes

New Fe(III) complexes have been synthesized by the reactions of ferric nitrate with Schiff base derived from 3-substituted phenyl-4-amino-5-hydrazino- 1,2,4-triazole and indoline-2,3-dione. All these complexes are soluble in DMF and DMSO; low molar conductance values indicate that they are non-electrolytes. Elemental analyses suggest that the complexes have 1:1 stoichiometry of the type [FeLn(H2O)(OH)]xH2O. Structural and spectroscopic properties have been studied on the basis of elemental analyses, infrared spectra, 1H and 13H NMR spectra, electronic spectra, magnetic measurements and FAB mass spectra. FT-IR, 1H and 13H NMR studies reveal that the ligand (Ln) exists in the tautomeric enol form in both the states with intramolecular hydrogen bonding. Magnetic moment and reflectance spectral studies reveal that an octahedral geometry has been assigned to all the prepared complexes. FRAP values indicate that all the compounds have a ferric reducing antioxidant power. The compounds 2 and 3 showed relatively high antioxidant activity while compound 1 and 4 shows poor antioxidant power. Also good antimicrobial activities of the complexes against Staphylococcus aureus, Bacillus subtilis, Serratia marcescens, Pseudomonas aeruginosa and Escherichia coli have been found compared to its free ligands.

Synthesis, spectral characterization and biological activity of zinc(II) complexes with 3-substituted phenyl-4-amino-5-hydrazino-1, 2, 4-triazole Schiff bases

New Zn(II) complexes have been synthesized by the reactions of zinc(II) acetate with Schiff bases derived from 3-substituted phenyl-4-amino-5-hydrazino- 1, 2, 4-triazole and benzaldehyde, 2-hydroxyacetophenone or indoline-2,3-dione. All these complexes are soluble in DMF and DMSO; low molar conductance values indicate that they are non-electrolytes. Elemental analyses suggest that the complexes have 1:1 stoichiometry of the type [ZnL(H2O)2], [ZnL′(OAc)2(H2O)2] (L = dianionic Schiff bases derived from 3-(substituted phenyl)-4-amino-5-hydrazino-1, 2, 4-triazole and 2-hydroxyacetophenone or indoline-2,3-dione; L′ = neutral Schiff bases derived from 3-(substituted phenyl)-4-amino-5-hydrazino-1, 2, 4-triazole and benzaldehyde) and they were characterized by FT-IR, 1H NMR, 13C NMR and FAB mass. All these Schiff bases and their complexes have also been screened for their antibacterial activities against Bacillus subtilis, Escherichia coli and antifungal activities against Colletotrichum falcatum, Aspergillus niger, Fusarium oxysporium and Carvularia pallescence by petriplates methods.