1350366-62-9Relevant academic research and scientific papers
Efficient syntheses of 1H-isochromen-1-ylmethylphosphonates via regioselective 6-endo-dig addition to carbon-carbon triple bond catalyzed by Pd(OAc)2
Zhao, Xiaona,Miao, Zhiwei,Chen, Ruyu
, p. 2357 - 2367 (2011)
An efficient, regioselective, palladium-catalyzed intramolecular cycloisomerization of dialkyl [(2-(2-ethynyl)phenyl)(2-hydroxyl)ethyl] phosphonate 6 is reported. The reactions proceed through a 6-endo-dig cyclization to afford 1H-isochromen-1-ylmethylphosphonates 7 in good to excellent yields using palladium(II) acetate as the catalyst in tetrahydrofuran at room temperature. Copyright Taylor & Francis Group, LLC.
