1350374-47-8Relevant articles and documents
Synthesis and structure-activity relationship of p-carborane-based non-secosteroidal vitamin D analogs
Fujii, Shinya,Kano, Atsushi,Songkram, Chalermkiat,Masuno, Hiroyuki,Taoda, Yoshiyuki,Kawachi, Emiko,Hirano, Tomoya,Tanatani, Aya,Kagechika, Hiroyuki
, p. 1227 - 1235 (2014)
1α,25-Dihydroxyvitamin D3 [1α,25(OH) 2D3: 1] is a specific modulator of nuclear vitamin D receptor (VDR), and novel vitamin D analogs are therapeutic candidates for multiple clinical applications. We recently developed non
Boron cluster-based development of potent nonsecosteroidal vitamin D receptor ligands: Direct observation of hydrophobic interaction between protein surface and carborane
Fujii, Shinya,Masuno, Hiroyuki,Taoda, Yoshiyuki,Kano, Atsushi,Wongmayura, Angsuma,et al.
, p. 20933 - 20941 (2012/03/07)
We report here the design and synthesis of a novel vitamin D receptor (VDR) agonist whose hydrophobic core structure is p-carborane (1,12-dicarba-closo- dodecaborane, an icosahedral carbon-containing boron cluster having remarkable thermal and chemical st