135040-16-3

Basic information

• Product Name: 2-Propen-1-one, 1,3-bis[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]-, (2E)-
• CAS NO: 135040-16-3
• Molecular Formula: C31H44O3
• Molecular Weight: 464.689
• Mol File: 135040-16-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-Propen-1-one, 1,3-bis[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]-, (2E)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Propen-1-one, 1,3-bis[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]-, (2E)-(135040-16-3)
• EPA Substance Registry System: 2-Propen-1-one, 1,3-bis[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]-, (2E)-(135040-16-3)

Safety Data

• Hazardous Substances Data: 135040-16-3(Hazardous Substances Data)

Upstream product

• 14035-33-7 1-(3,5-di-tert-butyl-4-hydroxyphenyl)ethanone 
• 1620-98-0 3,5-di-t-butyl-4-hydroxybenzaldehyde 

Downstream Products

• 721446-17-9 C₃₁H₄₆N₂O₂ 

Relevant articles and documents

Novel 3,5-diaryl pyrazolines and pyrazole as low-density lipoprotein (LDL) oxidation inhibitor

Compounds 4a-j and 5 were synthesized by cyclocondensation of 3a-j and hydrazine and showed significant LDL-antioxidant activities in the TBARS assay, the lag time of conjugated diene production, the relative electrophoretic mobility (REM) of ox-LDL, the apoB-100 fragmentation, and the macrophage-mediated LDL oxidation. Among compounds 4a-j and 5, 4a was found to be the most active compound as an inhibitor of LDL oxidation and 4a (IC 50=0.1μM) was 6-fold more potent than probucol (IC 50=0.6μM) in the TBARS assay.