1350426-06-0

Basic information

• Product Name: 2-(3-fluoro-4-isopropoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
• Synonyms: 2-(3-fluoro-4-isopropoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
• CAS NO: 1350426-06-0
• Molecular Weight: 280.147
• Mol File: 1350426-06-0.mol

Chemical Properties

• CAS DataBase Reference: 2-(3-fluoro-4-isopropoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(3-fluoro-4-isopropoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane(1350426-06-0)
• EPA Substance Registry System: 2-(3-fluoro-4-isopropoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane(1350426-06-0)

Safety Data

• Hazardous Substances Data: 1350426-06-0(Hazardous Substances Data)

Usage

Molecular structure

2-(3-fluoro-4-isopropoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane consists of a boron atom attached to a 4,4,5,5-tetramethyl-1,3,2-dioxaborolane core, with a 3-fluoro-4-isopropoxyphenyl group attached to the boron atom.

Type of compound

It is a boronic ester compound.

Usage

FTMD is used in organic synthesis and drug development as a building block in cross-coupling reactions to form carbon-carbon bonds, in the synthesis of pharmaceutical compounds, and has potential applications in materials science and bioconjugation.

Importance

It is a versatile and valuable chemical tool in the fields of organic chemistry and chemical biology.

Upstream product

• 202865-80-3 4-bromo-2-fluoro-1-isopropoxybenzene 
• 73183-34-3 bis(pinacol)diborane 
• 2105-94-4 4-bromo-2-fluorophenol 

Downstream Products

• 1408087-64-8 3-(3-fluoro-4-isopropoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine 
• 1408085-07-3 2-((4-Amino-3-(3-fluoro-4-isopropoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)methyl)-3-(3-fluorophenyl)-5-methoxy-4H-chromen-4-one 
• 1408085-09-5 2-((4-amino-3-(3-fluoro-4-isopropoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)methyl)-5-fluoro-3-(3-fluorophenyl)-4H-chromen-4-one 
• 1408085-14-2 2-(1-(4-amino-3-(3-fluoro-4-isopropoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)ethyl)-5-fluoro-3-(3-fluorophenyl)-4H-chromen-4-one 
• 1408087-20-6 2-(1-(4-amino-3-(3-fluoro-4-isopropoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)ethyl)-3-(3-fluorophenyl)-5-morpholino-4H-chromen-4-one 
• 1532533-67-7 TGR-1202 
• 1532533-69-9 (R)-2-(1-(4-amino-3-(3-fluoro-4-isopropoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)ethyl)-6-fluoro-3-(3-fluorophenyl)-4H-chromen-4-one 

Relevant articles and documents

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NOVEL COMPOUNDS AS MODULATORS OF PROTEIN KINASES

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NOVEL 3,5-DISUBSTITUTED-3H-IMIDAZO[4,5-B]PYRIDINE AND 3,5- DISUBSTITUTED -3H-[1,2,3]TRIAZOLO[4,5-B] PYRIDINE COMPOUNDS AS MODULATORS OF PROTEIN KINASES

The present invention provides, inter alia, compounds of formula I as protein kinase modulators, methods of preparing them, pharmaceutical compositions containing them and methods of treatment, prevention and/or amelioration of kinase mediated diseases or disorders with them.

NOVEL 3,5-DISUBSTITUED-3H-IMIDAZO[4,5-B]PYRIDINE AND 3,5- DISUBSTITUED -3H-[1,2,3]TRIAZOLO[4,5-B] PYRIDINE COMPOUNDS AS MODULATORS OF PROTEIN KINASES

The present invention provides, inter alia, compounds of formula ΙΑ,ΙΙΑ and III as protein kinase modulators, methods of preparing them, pharmaceutical compositions containing them and methods of treatment, prevention and/or amelioration of kinase mediated diseases or disorders with them.