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4-((4-(cyclopentylamino)-5-methylpyrimidin-2-yl)amino)benzonitrile is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

1350435-20-9

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1350435-20-9 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1350435-20-9 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,5,0,4,3 and 5 respectively; the second part has 2 digits, 2 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 1350435-20:
(9*1)+(8*3)+(7*5)+(6*0)+(5*4)+(4*3)+(3*5)+(2*2)+(1*0)=119
119 % 10 = 9
So 1350435-20-9 is a valid CAS Registry Number.

1350435-20-9Downstream Products

1350435-20-9Relevant academic research and scientific papers

Design, synthesis and biological evaluation of cycloalkyl arylpyrimidines (CAPYs) as HIV-1 NNRTIs

Gu, Shuang-Xi,Yang, Shi-Qiong,He, Qiu-Qin,Ma, Xiao-Dong,Chen, Fen-Er,Dai, Hui-Fang,Clercq, Erik De,Balzarini, Jan,Pannecouque, Christophe

, p. 7093 - 7099 (2011)

A series of 18 cycloalkyl arylpyrimidines (CAPYs) were designed from lead compounds diarylpyrimidines (DAPYs), synthesized and evaluated for in vitro anti-HIV activity. Among them, the compound 1p displayed potent anti-HIV-1 activity against WT HIV-1 with an EC50 value of 0.055 μM and a selectivity index (SI) >7290. The preliminary structure-activity relationship (SAR) of this new series of compounds was also investigated, which enriched the SAR of diarylpyrimidines (DAPYs).

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