1350451-51-2Relevant academic research and scientific papers
Click dimers to target HIV TAR RNA conformation
Kumar, Sunil,Kellish, Patrick,Robinson, W. Edward,Wang, Deyun,Appella, Daniel H.,Arya, Dev P.
experimental part, p. 2331 - 2347 (2012/06/29)
A series of neomycin dimers have been synthesized using "click chemistry" with varying functionality and length in the linker region to target the human immunodeficiency virus type 1 (HIV-1) TAR RNA region of the HIV virus. The TAR (Trans-Activation Respo
Recognition of HIV TAR RNA by triazole linked neomycin dimers
Kumar, Sunil,Arya, Dev P.
experimental part, p. 4788 - 4792 (2011/09/20)
A series of neomycin dimers have been synthesized using 'click chemistry' with varying linker functionality and length to target the TAR RNA region of HIV virus. TAR (trans activation response) RNA region, a 59 base pair stem loop structure located at 5′-
