1350477-15-4Relevant academic research and scientific papers
Synthesis of the (2S,4S)-stereoisomers of 4-(indol-1-yl) and 4-arylamino derivatives of 5-oxoproline, proline, and 2-hydroxymethylpyrrolidine
Vigorov,Nizova,Shalunova,Grishakov,Sadretdinova,Ganebnykh,Ezhikova,Kodess,Krasnov
, p. 873 - 881 (2011)
Nucleophilic substitution of the halogen atom in dimethyl (S)-4-bromoglutamate followed by removal of the protecting groups and closure of a lactam ring afforded (2S,4S)-4-(indolin-1-yl)-5-oxoproline. The indoline fragment was oxidized into the indole fra
