135054-71-6

Basic information

• Product Name: 4(R)-Hydroxy-6(S)-[(2-p-fluorophenyl-4-p-fluorophenylthio-6-isopropyl)phenoxymethyl]-3,4,5,6-tetrahydro-2H-pyran-2-one
• Synonyms: 4(R)-Hydroxy-6(S)-[(2-p-fluorophenyl-4-p-fluorophenylthio-6-isopropyl)phenoxymethyl]-3,4,5,6-tetrahydro-2H-pyran-2-one
• CAS NO: 135054-71-6
• Molecular Weight: 484.564
• Mol File: 135054-71-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 4(R)-Hydroxy-6(S)-[(2-p-fluorophenyl-4-p-fluorophenylthio-6-isopropyl)phenoxymethyl]-3,4,5,6-tetrahydro-2H-pyran-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 4(R)-Hydroxy-6(S)-[(2-p-fluorophenyl-4-p-fluorophenylthio-6-isopropyl)phenoxymethyl]-3,4,5,6-tetrahydro-2H-pyran-2-one(135054-71-6)
• EPA Substance Registry System: 4(R)-Hydroxy-6(S)-[(2-p-fluorophenyl-4-p-fluorophenylthio-6-isopropyl)phenoxymethyl]-3,4,5,6-tetrahydro-2H-pyran-2-one(135054-71-6)

Safety Data

• Hazardous Substances Data: 135054-71-6(Hazardous Substances Data)

Upstream product

• 135054-69-2 {(4R,6S)-6-[4'-Fluoro-5-(4-fluoro-phenylsulfanyl)-3-isopropyl-biphenyl-2-yloxymethyl]-2,2-dimethyl-[1,3]dioxan-4-yl}-acetic acid tert-butyl ester 
• 135054-68-1 (3R,5S)-6-<(methylsulfonyl)oxy>-3,5-O-isopropylidene-3,5-dihydroxyhexanoic acid tert-butyl ester 
• 131003-24-2 2-p-Fluorophenyl-4-p-fluorophenylthio-6-isopropylphenol 
• 124655-09-0 1,1-dimethylethyl (4R-cis)-6-hydroxymethyl-2,2-dimethyl-1,3-dioxane-4-acetate 
• 135054-70-5 tert.-Butyl 3(R),5(S)-dihydroxy-6-[(2-p-fluorophenyl-4-p-fluorophenylthio-6-isopropyl)phenoxy]hexanoate 

Downstream Products

• 136034-04-3 Sodium 3(R),5(S)-dihydroxy-6-[(2-p-fluorophenyl-4-p-fluorophenylthio-6-isopropyl)phenoxy]hexanoate 

Relevant articles and documents

4-hydroxytetrahydropyran-2-ones and the corresponding dihydroxycarboxylic acid derivatives, salts and esters and a process for their preparation

4-Hydroxytetrahydropyran-2-ones and the corresponding dihydroxycarboxylic acid derivatives, salts and esters, process for their preparation, their use as pharmaceuticals, and pharmaceutical preparations and precursors. Compounds of the formula I STR1 and the corresponding open-chain dihydroxycarboxylic acids of the formula II STR2 in which X, Y, R1, R2, R3, R4 and R5 have the meanings indicated, and also their pharmacologically tolerable salts with bases and their pharmacologically tolerable esters, processes for the preparation of these compounds, their use as pharmaceuticals and pharmaceutical preparations are described. In addition, compounds of the formula III STR3 in which R1, R2, R3, R4, R5, X and Y have the meanings indicated are described.