135055-48-0

Basic information

• Product Name: N-(2',4'-dinitrophenyl)-3-phenylpyridinium chloride
• Synonyms: N-(2',4'-dinitrophenyl)-3-phenylpyridinium chloride
• CAS NO: 135055-48-0
• Molecular Weight: 357.753
• Mol File: 135055-48-0.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: N-(2',4'-dinitrophenyl)-3-phenylpyridinium chloride(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2',4'-dinitrophenyl)-3-phenylpyridinium chloride(135055-48-0)
• EPA Substance Registry System: N-(2',4'-dinitrophenyl)-3-phenylpyridinium chloride(135055-48-0)

Safety Data

• Hazardous Substances Data: 135055-48-0(Hazardous Substances Data)

Upstream product

• 1008-88-4 3-phenylpyridine 
• 97-00-7 1-chloro-2,4-dinitro-benzene 

Downstream Products

• 165074-34-0 N-(phenylsulfonylimino)-3-phenylpyridinium ylide 
• 1033950-85-4 (2E,4E)-2-phenyl-5-N,N-dimethylamino-2,4-pentadien-1-al 
• 97-02-9 2,4-Dinitroanilin 
• 1170871-47-2 5-(2,4-dinitrophenylamino)-2-phenylpenta-2,4-dienal 
• 1170871-59-6 5-(2,4-dinitrophenylamino)-4-phenylpenta-2,4-dienal 
• 1321996-76-2 N-(4-methylbenzenesulfonylimino)-5-phenylpyridinium ylide 
• 1321996-78-4 N-(2-thiophenecarboylimino)-5-phenylpyridinium ylide 
• 1321996-77-3 N-(2-furoylimino)-5-phenylpyridinium ylide 
• 1222177-78-7 (6Z)-N-((2,E,4E)-5-(diethylamino)-2-phenylpenta-2,4-dienylidene)-2,4-dinitrobenzenamine 
• 135055-53-7 N-(4'-pyridylcarbonylimino)-3-phenylpyridinium ylide 
• 135055-54-8 N-(3'-pyridylcarbonylimino)-3-phenylpyridinium ylide 
• 135055-55-9 N-(2'-pyridylcarbonylimino)-3-phenylpyridinium ylide 
• 135055-65-1 N-(3'-pyridylcarbonylamino)-5-phenyl-1,2,3,6-tetrahydropyridine 

Relevant articles and documents

Synthesis of n-substituted carbonylamino-1,2,3,6-tetrahydropyridines as potential anti-inflammatory agents

Several N-substituted carbonyl/sulfonylamino-1,2,3,6-tetrahydropyridines (5a-i and 9a, b) were synthesized via sodium borohydride reduction of the corresponding N-substitutedimino-pyridinium ylides (4a-i and 8a, b) in absolute ethanol. Taylor &FrancisGroup, LLC.

Synthesis of δ-tributylstannyl-α,βγ, δ-unsaturated aldehydes from pyridines

(Equation Presented) Zincke aldehydes, which are readily available from the ring-opening reaction of pyridinium salts, are easily converted into δ-tributylstannyl-α,β,γ,δ-unsaturated aldehydes (stannyldienals) by the action of tributylstannyllithium. This reaction appears to proceed via 1,6-stannyllithium addition/elimination of lithium dialkylamide. Several stannyldienals of significant utility for the synthesis of polyene natural products have been made by this route, which proceeds in modest yields, but is successful on multigram scale using inexpensive reagents. Simple stannylenals and stannylenones are similarly available from the corresponding vinylogous amides.

Synthesis of Some N-(Phenylsulfonylamino)-1,2,3,6-tetrahydropyridines as Potential Anti-inflammatory Agents

Several N-(phenylsulfonylamino)-1,2,3,6-tetrahydropyridines were synthesized by substituting a sulfonyl group for the carbonyl group of N-(phenylcarbonylamino)-1,2,3,6-tetrahydropyridines 1 in order to investigate the effect of the substitution on the analgesic and anti-inflammatory activities. Nucleophilic attack of pyridine derivatives 2 on 1-chloro-2,4-dinitrobenzene 3 furnished the pyridinium chlorides 4. Compound 4 and benzenesulfonyl hydrazide 5 were reacted to give the 2,4-dinitroanilino derivatives 6. Hydrolysis of 6 furnished the ylides 7. Sodium borohydride reduction of ylides afforded the tetrahydropyridines 8. Compound 8c was found to be the most active anti-inflammatory agent and was as potent as indomethacin, the reference compound. Compound 8f had the most significant hyperglycemic activity.