1350616-26-0Relevant articles and documents
Efficient and convenient synthesis of spiroindolinone-quinazolines induced by stannous chloride
Hu, Yu,Wang, Man-Man,Chen, Hui,Shi, Da-Qing
experimental part, p. 9342 - 9346 (2011/12/14)
An efficient, convenient, one-pot synthesis of 1′H-spiro[indoline-3, 2′-quinazoline]-2,4′(3′H)-dione derivatives was accomplished in good yields via the novel reductive cyclization of 2-nitrobenzamides and isatins mediated by SnCl2·2H2O system. A variety of substrates can participate in the process with good yields, making this methodology have broad applicability. The structure of compound 3c has been confirmed by X-ray diffraction analysis.