135067-05-9

Basic information

• Product Name: 6-Perfluoroisopropyl-1-trimethylsiloxy-1-cyclohexene
• Synonyms: 6-Perfluoroisopropyl-1-trimethylsiloxy-1-cyclohexene
• CAS NO: 135067-05-9
• Molecular Weight: 338.341
• Mol File: 135067-05-9.mol

Chemical Properties

• CAS DataBase Reference: 6-Perfluoroisopropyl-1-trimethylsiloxy-1-cyclohexene(CAS DataBase Reference)
• NIST Chemistry Reference: 6-Perfluoroisopropyl-1-trimethylsiloxy-1-cyclohexene(135067-05-9)
• EPA Substance Registry System: 6-Perfluoroisopropyl-1-trimethylsiloxy-1-cyclohexene(135067-05-9)

Safety Data

• Hazardous Substances Data: 135067-05-9(Hazardous Substances Data)

Upstream product

• 677-69-0 perfluoroisopropyl iodide 
• 6651-36-1 1-(Trimethylsilyloxy)cyclohexene 

Relevant articles and documents

TRIETHYLBORANE INDUCED PERFLUOROALKYLATION OF SILYL ENOL ETHERS OR GERMYL ENOL ETHERS WITH PERFLUOROALKYL IODIDES

Reaction of perfluoralkyl iodides with silyl enol ethers mediated by Et3B in the presence of a base provides perfluoroalkylated silyl enol ethers.Meanwhile, treatment of germyl enol ethers with perfluoroalkyl iodides affords α-perfluoroalkyl ketones in good yields.

Triethylborane Induced Perfluoroalkylation of Silyl Enol Ethers and Ketene Silyl Acetals with Perfluoroalkyl Iodides

Reaction of perfluoroalkyl iodides with silyl enol ethers mediated by Et3B in the presence of base such as 2,6-dimethylpyridine provides mixtures of perfluoroalkylated trialkylsilyl enol ethers and α-perfluoroalkylated ketones.The yield and distribution of the products heavily depend on the nature of base employed.Treatment of a reaction mixture consisting of perfluoroalkylated silyl enol ether and α-perfluoroalkylated ketone with concd HCl in THF gives α-perfluoroalkylated ketone as a single product.Reaction of ketene silyl acetals with perfluoroalkyl iodides in the absence of base affords α-perfluoroalkylated esters in excellent yields.