1350719-28-6

Basic information

• Product Name: {(S)-2-methyl-1-[(S)-2-(5-phenyl-1H-imidazol-2-yl)pyrrolidine-1-carboline]propyl}carbamic acid methyl ester
• Synonyms: {(S)-2-methyl-1-[(S)-2-(5-phenyl-1H-imidazol-2-yl)pyrrolidine-1-carboline]propyl}carbamic acid methyl ester
• CAS NO: 1350719-28-6
• Molecular Weight: 370.451
• Mol File: 1350719-28-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: {(S)-2-methyl-1-[(S)-2-(5-phenyl-1H-imidazol-2-yl)pyrrolidine-1-carboline]propyl}carbamic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: {(S)-2-methyl-1-[(S)-2-(5-phenyl-1H-imidazol-2-yl)pyrrolidine-1-carboline]propyl}carbamic acid methyl ester(1350719-28-6)
• EPA Substance Registry System: {(S)-2-methyl-1-[(S)-2-(5-phenyl-1H-imidazol-2-yl)pyrrolidine-1-carboline]propyl}carbamic acid methyl ester(1350719-28-6)

Safety Data

• Hazardous Substances Data: 1350719-28-6(Hazardous Substances Data)

Upstream product

• 1252037-59-4 (S)-2-(5-phenyl-1H-imidazol-2-yl)-pyrrolidine-1-carboxylic acid tert-butyl ester 
• 944030-47-1 (S)-5-phenyl-2-(pyrrolidin-2-yl)-1H-imidazole 
• 111398-44-8 N-methoxycarbonyl-L-valine 

Relevant articles and documents

SUBSTITUTED AZOLES, ANTIVIRAL ACTIVE COMPONENT, PHARMACEUTICAL COMPOSITION, METHOD FOR PREPARATION AND USE THEREOF

The present invention relates to novel azoles, novel antiviral active components of the general formulas 1A and 1B, pharmaceutical composition, antiviral medicament, method for prophylaxis and treatment of viral diseases, particularly caused by hepatitis C viruses (HCV). In general formulas 1A and 1B wherein: solid lines with accompanying dotted lines () represent ordinary bond or double bond, provided that one of them is an ordinary bond, the other one is double bond; X and Y accept various meanings, one of them is—nitrogen, the other—oxygen, sulfur or NH group; R1 and R2—optionally the same radicals selected from 2-(R)- and (S)-substituted N-acyl pyrrolidine derivatives; N-methyl-N-[2-(R) and (S)-substituted 2,2-disubstituted acetamides; methyl[2-(R) and (S)-substituted ((methyl)amino)-(1-oxobutan-2-yl)-2-(R)-] and (S)-iso-propyl)-carbamates. A represents aliphatic C2-C8 biradical; dioxane, cyclo- and bicycloaliphatic, alkyloxyalkyl, alkyloxyalkylenoxyalkyl, alkenyloxyalkyl, alkynyloxyalkyl biradicals and their thioanaloges; aryl and thiophene alkynylcycloalkyl, alkynyldioxane, alkynylaryl, alkylthiophene, alkenylthiophene and alkynylthiophene, alkyloxyaryl, alkenyloxyaryl, alkynyloxyaryl, alkylthioaryl, alkenylthioaryl, alkynylthioaryl, cycloalkylthiophene, aryldioxane and thiophenyldioxane biradicals. B represents: aliphatic C2-C8 radical, including 1, 2 or 3 triple C≡C bonds; aryl and thiophene, alkynylcycloalkyl, alkynyldioxane, alkynylaryl, alkylthiophene, alkenylthiophene and alkynylthiophene, cycloalkylbenzene, 4-cycloalkylbiphenyl, bicycloalkylbenzene, 4-bicycloalkylbiphenyl, cycloalkylthiophene, aryldioxane and thiophenyldioxane radicals.