135080-78-3Relevant academic research and scientific papers
Addition of difluorocarbene to 3′,4′-unsaturated nucleosides: Synthesis of 2′-deoxy analogues with a 2-oxabicyclo[3.1.0]hexane framework
Nowak, Ireneusz,Cannon, John F.,Robins, Morris J.
, p. 532 - 537 (2007/10/03)
Treatment of protected 2′-deoxy-3′,4′-unsaturated nucleosides derived from adenosine and uridine with difluorocarbene [generated from bis(trifluoromethyl)mercury and sodium iodide] gave fused-ring 2,2-difluorocyclopropane compounds. Stereoselective α-face
SYNTHESIS OF 5'-O-PHOSPHONOMETHYL-2',3'-DIDEHYDRO-2',3'-DIDEOXYURIDINE BY USE OF P-METHOXYBENZYL AS A N3-PROTECTING GROUP.
Aerschot, A. Van,Jie, L.,Herdewijn, P.
, p. 1905 - 1908 (2007/10/02)
Uridine derivatives are protected at N3-position with a p-methoxybenzyl group under Mitsunobu conditions.Selective removal is possible with ceric ammonium nitrate.The otherwise difficult to obtain 5'-O-phosphonomethyl d4U was prepared using thi
