1350846-02-4Relevant academic research and scientific papers
Palladium-catalyzed benzylic substitution of benzyl carbonates with phosphorus nucleophiles
Makida, Yusuke,Usui, Kazumi,Ueno, Satoshi,Kuwano, Ryoichi
supporting information, p. 1814 - 1817 (2017/11/23)
A wide range of benzyl carbonates reacted with dimethyl phosphonate or diphenylphosphine oxide in the presence of the palladium catalyst, [Pd(η3-allyl)Cl]2DPEphos, to give dimethyl benzylphosphonates and benzyldiphenylphosphine oxides in high yields. The catalytic phosphonylation was applied to the one-pot synthesis of alkenes from the benzyl esters.
A general Pd-catalyzed α- And γ-benzylation of aldehydes for the formation of quaternary centers
Franzoni, Ivan,Guénée, Laure,Mazet, Clément
supporting information, p. 6338 - 6343 (2015/06/08)
A palladium-catalyzed benzylation of α-branched aldehydes has been developed using benzyl methyl carbonates. The method gives access to congested quaternary centers in the vicinity of one of the most sensitive carbonyl functionalities and displays unprecedented generality with respect to both coupling partners. Evidence for the direct involvement of a Pd-η3-benzyl intermediate is provided. Extension of this strategy to the γ-benzylation of α,β-unsaturated aldehydes is further demonstrated.
Palladium-catalyzed C3-benzylation of indoles
Zhu, Ye,Rawal, Viresh H.
supporting information; experimental part, p. 111 - 114 (2012/03/07)
A general method for regioselective C3-benzylation of indoles has been developed. Various 3-substituted indoles and benzyl methyl carbonates with different electronic properties react under mild conditions to afford a diverse range of 3-benzylindolenine products in good yields.
Intramolecular SN′-type aromatic substitution of benzylic carbonates at their para-position
Ueno, Satoshi,Komiya, Sadakazu,Tanaka, Takeshi,Kuwano, Ryoichi
supporting information; experimental part, p. 338 - 341 (2012/03/10)
The benzylic carbonates, which connect with an active methine through an o-phenylene tether at their meta-position, are cyclized by Pd(η3- C3H5)Cp-S-Phos catalyst, yielding 3-methyl-9,10- dihydrophenanthrenes. In the catal
