135085-99-3

Upstream product

• 555-16-8 4-nitrobenzaldehdye 
• 135085-98-2 (3-Methoxy-2-methylene-butyl)-trimethyl-silane 

Downstream Products

• 135086-19-0 (1R,3S,4R)-4-Methoxy-1-(4-nitro-phenyl)-pentane-1,3-diol 
• 135086-19-0 (1R,3R,4R)-4-Methoxy-1-(4-nitro-phenyl)-pentane-1,3-diol 
• 135086-19-0 (1R,3S,4S)-4-Methoxy-1-(4-nitro-phenyl)-pentane-1,3-diol 
• 135086-19-0 (1R,3R,4S)-4-Methoxy-1-(4-nitro-phenyl)-pentane-1,3-diol 

Relevant academic research and scientific papers

Optically active allylic tin reagent as an enantio-divergent synthon of isoprenoids via remote and divergent asymmetric induction

(S)-2-(1-Hydroxymethyl)allyltin (1a) can be prepared in high enantiomeric purity. When its methylated and acetylated derivatives are allowed to add to aldehydes with the help of i-PrOTiCl3 and SnCl4, syn- and anti-homoallylic alcohol

DIVERGENTLY STEREOCONTROLLED REACTION OF AN ALLYLIC SILANE BEARING AN ASYMMETRIC ETHEREAL CARBON TOWARD ALDEHYDES

Lewis acid mediated allylation of aldehydes by an allylsilane bearing an asymmetric ethereal functionality proceeded in divergently stereocontrolled manners, i. e., TiCl4 afforded the syn isomer, whereas BF3*OEt2 afforded the anti isomer predominantly.