1350850-29-1Relevant articles and documents
Electronic-state switching strategy in the photochemical synthesis of indanones from o-methyl phenacyl epoxides
Stacko, Peter,Solomek, Tomas,Klan, Petr
, p. 6556 - 6559 (2011)
An electronic excited-state switching strategy has been utilized to control the selectivity of a key photochemical step in the total synthesis of indanorine. The excited-state character of 4, 5-dimethoxy-2-methylphenacyl epoxide was changed from an unfavorable 3φ , φ * state to a productive 3n, φ * state by a temporary structural modification, resulting in a relatively efficient and high-yielding formation of an indanone derivative. The corresponding structural modification was selected on the basis of quantum chemical calculations prior to the synthesis.