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1350883-45-2

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1350883-45-2 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1350883-45-2 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,5,0,8,8 and 3 respectively; the second part has 2 digits, 4 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1350883-45:
(9*1)+(8*3)+(7*5)+(6*0)+(5*8)+(4*8)+(3*3)+(2*4)+(1*5)=162
162 % 10 = 2
So 1350883-45-2 is a valid CAS Registry Number.

1350883-45-2Downstream Products

1350883-45-2Relevant academic research and scientific papers

Synthesis and biological evaluation of arylated novobiocin analogs as Hsp90 inhibitors

Kusuma, Bhaskar Reddy,Duerfeldt, Adam S.,Blagg, Brian S.J.

, p. 7170 - 7174 (2012/01/15)

Novobiocin analogs lacking labile glycosidic ether have been designed, synthesized and evaluated for Hsp90 inhibitory activity. Replacement of the synthetically complex noviose sugar with simple aromatic side chains produced analogs that maintain moderate cytotoxic activity against MCF7 and SkBR3 breast cancer cell-lines. Rationale for the preparation of des-noviose novobiocin analogs in addition to their synthesis and biological evaluation are presented herein.

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