1350900-72-9Relevant academic research and scientific papers
Evaluation of 18F-labeled benzodioxine piperazine-based dopamine D4 receptor ligands: Lipophilicity as a determinate of nonspecific binding
Kügler, Fabian,Sihver, Wiebke,Ermert, Johannes,Hübner, Harald,Gmeiner, Peter,Prante, Olaf,Coenen, Heinz H.
, p. 8343 - 8352 (2011)
Derivatization of the putative neuroleptic 1-(2,3-dihydrobenzo[1,4]dioxin- 6-yl)-4-(4-fluorobenzyl)-piperazine (3a) led to a series of new dopamine receptor D4 ligands displaying high affinity (Ki = 1.1-15 nM) and D2/Dsub
