1350909-99-7

Basic information

• Product Name: tert-butyl (RS,E)-4-(N,N-dibenzylamino)-6-methylhept-2-enoate
• Synonyms: tert-butyl (RS,E)-4-(N,N-dibenzylamino)-6-methylhept-2-enoate
• CAS NO: 1350909-99-7
• Molecular Weight: 393.569
• Mol File: 1350909-99-7.mol

Chemical Properties

• CAS DataBase Reference: tert-butyl (RS,E)-4-(N,N-dibenzylamino)-6-methylhept-2-enoate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl (RS,E)-4-(N,N-dibenzylamino)-6-methylhept-2-enoate(1350909-99-7)
• EPA Substance Registry System: tert-butyl (RS,E)-4-(N,N-dibenzylamino)-6-methylhept-2-enoate(1350909-99-7)

Safety Data

• Hazardous Substances Data: 1350909-99-7(Hazardous Substances Data)

Upstream product

• 328-39-2 LEUCINE 
• 86302-43-4 (tert-Butoxycarbonylmethylene)triphenylphosphorane 

Downstream Products

• 1350910-38-1 tert-butyl (3S,4S,αR)-3-[N-benzyl-N-(α-methylbenzyl)amino]-4-(N,N-dibenzylamino)-6-methylheptanoate 
• 1350910-19-8 tert-butyl (3R,4R,αS)-3-[N-3',4'-dimethoxybenzyl-N-(α-methylbenzyl)amino]-4-(N,N-dibenzylamino)-6-methylheptanoate 

Relevant articles and documents

Parallel kinetic resolution of acyclic γ-amino-α,β- unsaturated esters: Application to the asymmetric synthesis of 4-aminopyrrolidin-2-ones

Conjugate addition of a 50:50 pseudoenantiomeric mixture of lithium (R)-N-benzyl-N-(α-methylbenzyl)amide and lithium (S)-N-3,4- dimethoxybenzyl-N-(α-methylbenzyl)amide to a range of racemic acyclic γ-amino-α,β-unsaturated esters (derived from the corresponding α-amino acids) effects their efficient parallel kinetic resolution, allowing the preparation of enantiopure β,γ-diamino esters. The β,γ-diamino ester products of these reactions are readily converted into the corresponding substituted 4-aminopyrrolidin-2-ones via N-debenzylation and cyclization.