1350915-76-2Relevant academic research and scientific papers
Design, synthesis and in vitro PDE4 inhibition activity of certain quinazolinone derivatives for treatment of asthma
Elansary, Afaf K.,Kadry, Hanan H.,Ahmed, Eman M.,Sonousi, Amr Sayed Motawi
, p. 3327 - 3335 (2013/02/23)
In this study, a novel series of quinazolinone derivatives analogue to nitraquazone structure were synthesized. The compounds tested for their inhibitory activity against phosphodiesterase 4B revealed that compound 6d shows promising inhibitory activity comparable to that of Rolipram, whereas compounds 6a and 6c exhibited moderate inhibitory activity. Springer Science+Business Media, LLC 2011.
