1350929-54-2

Basic information

• Product Name: dimethyl 1-(2-phenylcyclohex-2-enyl)-1H-1,2,3-triazole-4,5-dicarboxylate
• CAS NO: 1350929-54-2
• Molecular Weight: 341.367
• Mol File: 1350929-54-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: dimethyl 1-(2-phenylcyclohex-2-enyl)-1H-1,2,3-triazole-4,5-dicarboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: dimethyl 1-(2-phenylcyclohex-2-enyl)-1H-1,2,3-triazole-4,5-dicarboxylate(1350929-54-2)
• EPA Substance Registry System: dimethyl 1-(2-phenylcyclohex-2-enyl)-1H-1,2,3-triazole-4,5-dicarboxylate(1350929-54-2)

Safety Data

• Hazardous Substances Data: 1350929-54-2(Hazardous Substances Data)

Upstream product

• 101471-08-3 6-Azido-1-phenyl-1-cyclohexene 
• 762-42-5 dimethyl acetylenedicarboxylate 
• 771-98-2 1-Phenylcyclohexene 
• 40940-63-4 1-phenyl-2-bromo-1-hydroxycyclohexane 
• 40940-64-5 (±)-6-bromo-1-phenylcyclohex-1-ene 

Relevant articles and documents

Efficient synthesis and in vitro antitubercular activity of 1,2,3-triazoles as inhibitors of Mycobacterium tuberculosis

Efficient and rapid synthesis of 1,2,3-triazole derivatives has been achieved via Huisgen's 1,3-dipolar cycloaddition between alkyl/arylazides and diethyl/dimethyl acetylenedicarboxylate in excellent yields under solvent-free conditions. The environmentally friendly solvent-free protocol overcomes the limitations associated with the prevailing time-consuming solution phase protocols and affords the triazoles just in 1-3 min. In vitro antitubercular activity of these triazoles was screened against Mycobacterium tuberculosis H37Rv strain. Four of the compounds showed MIC in the range of 1.56-3.13 μg/mL proving their potential activity.