1350971-27-5Relevant articles and documents
Stereodivergency in catalytic asymmetric conjugate addition reactions of glycine (Ket)imines
Kim, Hun Young,Li, Jian-Yuan,Kim, Sungkyung,Oh, Kyungsoo
, p. 20750 - 20753 (2011)
Stereodivergent catalytic asymmetric conjugate reactions of glycine (ket)imines with nitroalkenes have been achieved using various chiral catalyst systems derived from a multidentate amino alcohol (1). The stepwise nature of the [3 + 2] cycloaddition reactions of N-metalated azomethine ylides has also been demonstrated by highly enantio- and diastereoselective syntheses of exo-5 and endo-8 from the respective syn-4 and anti-7 conjugate addition products in a one-pot tandem fashion.