1351066-96-0Relevant articles and documents
Nickel-catalyzed direct alkynylation of C(sp2)-H bonds of amides: An "inverse Sonogashira strategy" to ortho-alkynylbenzoic acids
Landge, Vinod G.,Shewale, Chinmay H.,Jaiswal, Garima,Sahoo, Manoj K.,Midya, Siba P.,Balaraman, Ekambaram
, p. 1946 - 1951 (2016)
Nickel-catalyzed direct alkynylation of C(sp2)-H bonds of amides using commercially available, inexpensive 8-aminoquinoline as a removable bidentate directing group is described. The present ortho-alkynylation has a broad substrate scope, funct
Nickel-Catalyzed Alkynylation of a C(sp2)-H Bond Directed by an 8-Aminoquinoline Moiety
Yi, Jun,Yang, Li,Xia, Chungu,Li, Fuwei
, p. 6213 - 6221 (2015/06/30)
An efficient nickel catalyst system for the direct ortho C-H alkynylation of the amides has been successfully developed with the directing assistance of 8-aminoquinoline. It was found that the flexible bis(2-dimethylaminoethyl) ether (BDMAE) ligand was cr