1351163-92-2Relevant articles and documents
Discovery of new orally active prostaglandin D2 receptor antagonists
Iwahashi, Maki,Naganawa, Atsushi,Kinoshita, Atsushi,Shimabukuro, Atsushi,Nishiyama, Toshihiko,Ogawa, Seiji,Matsunaga, Yoko,Tsukamoto, Kohki,Okada, Yutaka,Matsumoto, Ryoji,Nambu, Fumio,Oumi, Rie,Odagaki, Yoshihiko,Katagi, Jun,Yano, Koji,Tani, Kousuke,Nakai, Hisao,Toda, Masaaki
, p. 6935 - 6948 (2012/01/05)
To identify an orally available drug candidate, a series of 3-benzoylaminophenylacetic acids were synthesized and evaluated as prostaglandin D2 (PGD2) receptor antagonists. Some of the compounds tested were found to exhibit excellent