135134-19-9

Basic information

• Product Name: 3-bromo-1-hydroxy-1-cyclohexyl-1-phenyl-2-propanone
• Synonyms: 3-bromo-1-hydroxy-1-cyclohexyl-1-phenyl-2-propanone
• CAS NO: 135134-19-9
• Molecular Weight: 311.219
• Mol File: 135134-19-9.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 3-bromo-1-hydroxy-1-cyclohexyl-1-phenyl-2-propanone(CAS DataBase Reference)
• NIST Chemistry Reference: 3-bromo-1-hydroxy-1-cyclohexyl-1-phenyl-2-propanone(135134-19-9)
• EPA Substance Registry System: 3-bromo-1-hydroxy-1-cyclohexyl-1-phenyl-2-propanone(135134-19-9)

Safety Data

• Hazardous Substances Data: 135134-19-9(Hazardous Substances Data)

Upstream product

• 52215-12-0 pyrrolidone hydrotribromide 
• 28192-98-5 1-cyclohexyl-1-hydroxy-1-phenylpropan-2-one 

Relevant articles and documents

MUSCARINIC RECEPTOR ANTAGONISTS

This present invention generally relates to muscarinic receptor antagonists, which are useful, among other uses, for the treatment of various diseases of the respiratory, urinary and gastrointestinal systems mediated through muscarinic receptors. The inve

1-Aryl-1-hydroxy-1-substituted-3-(4-substituted-1-piperazinyl)-2-propanones and their use in treatment of neurogenic bladder disorders

Compounds are disclosed having the formula (I): in which R1is a C1 to C12 alkyl, said alkyl being straight or branched chain, saturated or unsaturated, monosubstituted or unsubstituted, said substituents being selected from piperidine, pyrrolidine, morpholine, thiomorpholine or cycloalkyl of 3 to 7 carbons, a cycloalkyl of 3 to 9 carbons, a lower alkylcycloalkyl of 4 to 9 carbons, or a polycycloalkyl of 2 to 3 rings containing 7 to 12 carbons; R2is hydrogen, phenyl, phenyl singly or multiply substituted with halogen, hydroxy, lower alkoxy, methylene dioxy, nitro, lower alkyl or trifluoromethyl, lower alkyl, said alkyl being branched chain or straight, saturated, unsaturated, or cyclic and substituted or unsubstituted, said substituents being selected from thienyl, pyrrolyl, pyridyl, furanyl, hydroxy, lower alkoxy, or acetoxyalkyl wherein the alkyl group has 1 to 3 carbons, phenyl, phenyl substituted with halogen, hydroxy, lower alkoxy, lower alkyl, nitro, methylene dioxy or trifluoromethyl, Phis phenyl or phenyl para-substituted by halogen, lower alkyl, lower alkoxy or trifluoromethyl; and the pharmaceutically acceptable nontoxic salts thereof. The preparation of the compounds, pharmaceutical compositions containing them and their use in the treatment of neurogenic bladder disorder are also enclosed.