135144-51-3

Upstream product

• 135144-50-2 [(E)-(1R,4R)-5-Benzyloxy-2-(tert-butyl-dimethyl-silanyloxy)-3-fluoro-1,4-dimethyl-pent-2-enyl]-trityl-amine 
• 63930-46-1 (S)-3-benzyloxy-2-methylpropan-1-ol 
• 63930-47-2 (2R)-3-bromo-2-[(methylpropyloxy)methyl]benzene 
• 81927-55-1 O-benzyl 2,2,2-trichloroacetimidate 
• 56850-58-9 methyl (2R)-3-(benzyloxy)-2-methylpropanoate 
• 135144-47-7 (2R,5S)-6-Benzyloxy-5-methyl-2-(trityl-amino)-hexan-3-one 
• 135144-49-9 (2R,5R)-6-Benzyloxy-4-fluoro-5-methyl-2-(trityl-amino)-hexan-3-one 
• 135144-56-8 [(Z)-(1R,4S)-5-Benzyloxy-2-(tert-butyl-dimethyl-silanyloxy)-1,4-dimethyl-pent-2-enyl]-trityl-amine 

Relevant academic research and scientific papers

Synthesis of the Monofluoro Ketone Peptide Isostere

A synthetic method for the construction of monofluoro ketone peptide isosteres has been realized.The methodology has been employed in a synthesis of the fluoro ketone replacement for the natural substrate for D,D-carboxypeptidase-transpeptidase.