1351557-17-9

Basic information

• Product Name: 11-(4-bromophenyl)-6-methyl-6H-indolo[2,3-b]quinoline
• Synonyms: 11-(4-bromophenyl)-6-methyl-6H-indolo[2,3-b]quinoline
• CAS NO: 1351557-17-9
• Molecular Weight: 387.278
• Mol File: 1351557-17-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 11-(4-bromophenyl)-6-methyl-6H-indolo[2,3-b]quinoline(CAS DataBase Reference)
• NIST Chemistry Reference: 11-(4-bromophenyl)-6-methyl-6H-indolo[2,3-b]quinoline(1351557-17-9)
• EPA Substance Registry System: 11-(4-bromophenyl)-6-methyl-6H-indolo[2,3-b]quinoline(1351557-17-9)

Safety Data

• Hazardous Substances Data: 1351557-17-9(Hazardous Substances Data)

Upstream product

• 603-76-9 1-methylindole 
• 370851-82-4 2-(4-bromobenzoyl)-1-(4-methylphenylsulfonamido)benzene 

Relevant articles and documents

One-pot access to indolo[2,3- b]quinolines by electrophile-triggered cross-amination/friedel-crafts alkylation of indoles with 1-(2-tosylaminophenyl) ketones

Activation of C2 and C3 of indoles by molecular iodine (I2) and base followed by in situ reaction with 1-(2-tosylaminophenyl)ketones or 2-tosylaminobenzaldehyde can afford highly substituted indolo(2,3-b)quinolines in moderate to excellent yields (up to 99%). The reaction provides a metal-free selective difunctionalization of indoles. The synthetic potential of the protocol has been illustrated by the synthesis of neocryptolepine and its 11-methyl analogue.