1351761-98-2

Basic information

• Product Name: 2-[2-methoxy-4-(morpholine-4-carbonyl)-phenylamino]-4-methylamino-pyrimidine-5-carbonitrile
• Synonyms: 2-[2-methoxy-4-(morpholine-4-carbonyl)-phenylamino]-4-methylamino-pyrimidine-5-carbonitrile
• CAS NO: 1351761-98-2
• Molecular Weight: 368.395
• Mol File: 1351761-98-2.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-[2-methoxy-4-(morpholine-4-carbonyl)-phenylamino]-4-methylamino-pyrimidine-5-carbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[2-methoxy-4-(morpholine-4-carbonyl)-phenylamino]-4-methylamino-pyrimidine-5-carbonitrile(1351761-98-2)
• EPA Substance Registry System: 2-[2-methoxy-4-(morpholine-4-carbonyl)-phenylamino]-4-methylamino-pyrimidine-5-carbonitrile(1351761-98-2)

Safety Data

• Hazardous Substances Data: 1351761-98-2(Hazardous Substances Data)

Upstream product

• 3177-24-0 2,4-dichloropyrimidine-5-carbonitrile 
• 2486-69-3 3-methoxy-4-aminobenzoic acid 
• 389606-74-0 2-chloro-4-(methylamino)pyrimidine-5-carbonitrile 
• 557-21-1 zinc(II) cyanide 
• 1351759-14-2 (4-(5-bromo-4-(methylamino)pyrimidin-2-ylamino)-3-methoxyphenyl)(morpholino)methanone 

Relevant articles and documents

2-PHENYLAMINOPYRIMIDINE DERIVATIVES AS KINASE LRRK2 MODULATORS FOR THE TREATMENT OF PARKINSON'S DISEASE

Specific Compounds of formula (I): or pharmaceutically acceptable salts thereof, wherein m, X, R, R2, R3, R, R6 and R7 are as defined herein. Also disclosed are methods of making the compounds and using the compounds for treatment of diseases associated with LRRK2 receptor, such as Parkinson's disease.

AMINOPYRIMIDINE DERIVATIVES AS LRRK2 INHIBITORS

Compounds of the formula I: or pharmaceutically acceptable salts thereof, wherein m, n. X, R1, R2, R3, R5, R6 and R7 are as defined herein. Also disclosed are methods of making the compound