135190-52-2Relevant academic research and scientific papers
Amide-based protecting/radical translocating (PRT) groups. Generation of radicals adjacent to carbonyls by 1,5-hydrogen transfer reactions of o-iodoanilides
Curran, Dennis P.,Yu, Hosung,Liu, Hongtao
, p. 7343 - 7366 (2007/10/02)
The o-iodoanilide group is shown to be broadly useful for the generation and subsequent reactions of radicals adjacent to carboxyl groups. The results indicate that this group is one of the best 'protecting/radical translocating' (PRT) groups introduced t
Radical Translocation Reactions of o-Iodoanilides: The Use of Carbon-Hydrogen Bonds as Precursors of Radicals Adjacent to Carbonyl Groups
Curran, Dennis P.,Abraham, Ann C.,Liu, Hongtao
, p. 4335 - 4337 (2007/10/02)
The treatment of o-iodoanilides with tributyltin hydride results in radical generation followed by rapid translocation to produce radicals adjacent to carbonyls.These radicals participate in cyclization and asymmetric addition reactions.
