1351926-90-3 Usage
General Description
T338C Src-IN-1 is a potent and selective inhibitor of the protein kinase Src, which plays a key role in regulating cell growth, survival, and metastasis. This chemical compound has been designed to specifically block the activity of Src and has shown promising anti-cancer activity in preclinical studies. T338C Src-IN-1 is also known for its ability to inhibit the growth and proliferation of cancer cells, making it a potential candidate for the development of targeted cancer therapies. Additionally, T338C Src-IN-1 has been shown to have favorable pharmacokinetic properties, which may further support its potential as a therapeutic agent for the treatment of cancer and other related diseases.
Check Digit Verification of cas no
The CAS Registry Mumber 1351926-90-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,5,1,9,2 and 6 respectively; the second part has 2 digits, 9 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 1351926-90:
(9*1)+(8*3)+(7*5)+(6*1)+(5*9)+(4*2)+(3*6)+(2*9)+(1*0)=163
163 % 10 = 3
So 1351926-90-3 is a valid CAS Registry Number.
1351926-90-3Relevant articles and documents
METHODS AND COMPOSITIONS FOR KINASE INHIBITION
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Paragraph 0340; 0341, (2013/06/05)
The present invention sets forth a new chemical genetic approach for engineering kinase enzymes with a cysteine gatekeeper residue as well as for developing electrophilic inhibitors thereto. The present invention also provides a Src proto-oncogenic tyrosine kinase with a cysteine gatekeeper that recapitulates wild type activity and can be irreversibly inhibited both in vitro and in cells. The present invention also provides methods and compositions for modulating kinases and for treating kinase-associated diseases.
