1351987-84-2Relevant academic research and scientific papers
Chemical and enzymatic synthesis of 2-(2-carbamoylethyl)- and 2-(2-carboxyethyl)aziridines and their conversion into δ-lactams and γ-lactones
Vervisch, Karel,D'Hooghe, Matthias,Rutjes, Floris P. J. T.,De Kimpe, Norbert
supporting information; experimental part, p. 106 - 109 (2012/02/14)
Treatment of 1-arylmethyl-2-(2-cyanoethyl)aziridines with a nitrile hydratase afforded the corresponding 2-(2-carbamoylethyl)aziridines, which underwent rearrangement into 5-hydroxypiperidin-2-ones upon heating under microwave irradiation. In addition, tr
